The Ozempic Effect: Navigating GLP-1 Receptor Agonists and Oral Health in Modern Dental Practice

GLP-1 receptor agonists are reshaping dental practice across Saudi Arabia. Nearly 1 in 5 overweight adults has used semaglutide — mostly for weight loss, without endocrinological oversight. This evidence-graded review separates pharmacovigilance findings from animal models, presents the bidirectional GLP-1/periodontitis biology, and gives clinicians a protocol built on what the evidence actually supports.

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